Istiyono is one of the painting artists who has visual characteristics in terms of deforming anatomy. The creative process to find his visual characteristics is need to know. The Aims of this research is to 1)  Describing the profile and the journey of Istiono’s life. 2) Describes Istiyono’s creative process  and  media work. 3) Analyze the visual characteristics of anatomical deformation in  Istiyono's paintings. This research is qualitative-descriptive research, so that data collection techniques are done by observation, interview, and documentation. The results of the study are 1) Istiyono is a autodidact artist was born in Nganjuk, September 27, 1963, who is productive in his work, had been active in Koperjati community, and founded Jongaco community in Nganjuk. 2) Istiyono's creative process in finding his visual characteristics is greatly influenced by the course of his life. Istiyono works more on conventional media by doing anatomical deformation, and combined three styles: realism, impressionism, and deformative forms, in all of his paintings. According to Rego (one of Nganjuk's artists) that identity is very strong attached to Istiyono. There has never been an artist with visual characteristics like Istiyono in Nganjuk Regency. 3) Based on the results of the analysis, karachteristic visual characteristic of Istiyono’s anatomical deformation are: the proportion of the head is reduced, tilted head gestures, tapered face on the chin, long neck, slim waist, extended the proportion of hands, pointed wrist, proportion of legs extended, enlarged hips, calves made prominent and tapering up to the ankle.

 Keywords: Visual Characteristics, Anatomical Deformation, Istiyono